Kwon Laboratory

Yonsei University College of Medicine, department of microbiology

We are studying immune cell function in homeostatic (healthy) Vs. non-homeostatic conditions
(autoimmune, cancer and neurodevelopmental disorders etc.)

About


     The Immune system is controlled by a specific set of regulatory and effector elements that have to be finely and constantly tuned to maintain its homeostasis throughout the longevity.  ‘Immunity’ encompasses active processes to protect against internal and/or external threaten such infection. As the counterpart of immunity, immune system develop exquisite mechanism, known as ‘Tolerance’, which actively induce a state of unresponsiveness of the immune system to various substance that have the capacity to elicit immune responses.

     The balance between these distinct immune compartments, called ‘Immunological homeostasis’, is exquisitely retained in a healthy individual and the breakdown of this symmetry can trigger inflammation driving much human pathology and disease, including autoimmune diseases, cancer and, potentially, neurodevelopmental disorders. Accordingly, we are very interested in uncovering novel mechanisms controlling function and development of immune cells, and how the failure of these mechanisms lead to the development and progression and inflammatory disorders.  Specifically, we aim to identify host- (especially immune and neuronal) and bacteria-factors that affect immunological homeostasis in normal and diseases condition and, eventually, to apply these to help with the treatment of human inflammatory disorders such as autoimmunity, cancer, and neurodevelopmental disorders.

                                            Highly motivated students and postdoctoral candidates are encouraged to apply!!
                                                         If interested, send an email to aspirationpassion@gmail.com


Research


Publication


Journal Club


Team


Ho-Keun Kwon

Professor

Kichun Kim

Post-doctor

Hyun-Woo Lee

Intern

Seo-Hyun Kim

Intern

Julie Choi

Alumni


News / Event


Contact Us


  • Room 246-11, Department of microbiology, Yonsei university college of medicine, 107-11 Sinchon-dong, Seodaemun-gu, Seoul, South Korea (Zip code: 120-752)
  • The Kwon Lab is located on the 2nd floor of YonSei University College of Medicine campus. Department of Microbiology